Oct 30, 2023 · 1/2. Synonyms: none. Endochondral ossification is one of the two ways by which bone is formed. The process of bone formation and development begins as an embryo and continues until early adulthood. Endochondral ossification occurs in the long bones around the 6th embryonic week. It involves the formation of hyaline cartilage precursors from ... Start studying intramembranous ossification steps. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Step 4. Spicules unite to form trabeculae of spongy bone surrounded by endosteum. Step 5. Remodeling of spongy bone forms compact bone with periosteum around. outer surface. Step 6. Study with Quizlet and memorize flashcards containing terms like Mesenchymal cells differentiate into osteoblast, Osteoblasts secrete matrix, Osteoblasts surrounded ... Figure 6.4.1 – Intramembranous Ossification: Intramembranous ossification follows four steps. (a) Mesenchymal cells …Step 1. Intramembranous ossification is one of the two critical phases of the gnathostome (apart from chondr... Connective tissue on the surface of each developing structure forms a periosteum Osteoblasts deposit bone matrix, forming spongy bone tissue Partially differentiated cells enlarge and differentiate into osteoblasts Osteoblasts become ...1. Both processes form compact bone. Arrange the following events in endochondral ossification in proper sequence: (1)Cartilage matrix is calcified and chondrocytes die. (2)Chondrocytes hypertrophy. (3)Cartilage model is formed. (4)Osteoblasts deposit bone on the surface of the calcified cartilage called the primary ossification center.Partially. Intramembranous Ossification Correctly sequence the steps of intramembranous ossification. Partially differentiated cells enlarge and differentiate into osteoblasts. Osteoblasts on the inside of the periosteum deposit compact bone over the spongy bone Connective tissue on the surface of each developing structure forms a …Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification? Ossification center develops > Calcification > Formation of trabeculae > Development of new periosteum. During endochondral ossification in a fetus, bones initially develop as a cartilage model that was formed from ...[1] Light micrograph of a nidus consisting of osteoprogenitor cells that are displaying a prominent Golgi apparatus. The process of intramembranous ossification starts when a small group of adjacent MSCs begin to …Intramembranous ossification is complete by the end of the adolescent growth spurt, while endochondral ossification lasts into young adulthood. The flat bones of the face, most of the cranial bones, and a good deal of the clavicles (collarbones) are formed via intramembranous ossification, while bones at the base of the skull and the …Endochondral ossification takes much longer than intramembranous ossification. Bones at the base of the skull and long bones form via endochondral ossification. In a long bone, for example, at about 6 to 8 weeks after conception, some of the mesenchymal cells differentiate into chondrocytes (cartilage cells) that form the cartilaginous skeletal ...Endochondral Ossification. Skip to main content. Anatomy & Physiology Start typing, then use the up and down arrows to select an option from the list. ... Steps of Muscle Contraction. 1m. 10. Muscles 1h 11m. Worksheet. Origin and Insertion. 11m. Muscle Actions. 15m. ... Intramembranous Ossification. Medic Tutorials - Medicine and Language. 953 ...Put the steps in endochondral ossification in order from beginning to end of the process. 1.Capillaries and osteoblasts penetrate the cartilage and invade the central region; osteoblasts begin producing spongy bone at the primary center of ossification; bone formation then spreads along the shaft toward both ends of the cartilaginous model. 2.As …Intramembranous ossification. Intramembranous ossification forms flat and irregular bones. In this process, mesenchymal cells differentiate directly into …3. Capillaries and osteoblasts migrate into the epiphysis, creating secondary ossification centers. 4. Blood vessels grow around the edges of the cartilage, and the cells of the perichondrium convert to osteoblasts. The shaft of the cartilage then becomes ensheathed in a superficial layer of bone. 5.Study with Quizlet and memorize flashcards containing terms like Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification? A) Ossification center develops > Calcification > Formation of trabeculae > Development of new periosteum. B) Calcification > Ossification center develops > …epiphyseal plates. which bone would be formed by the process of intramembranous ossification? a. vertebra of the spine. b. frontal bone of the forehead. c. mandible of the lower jaw. d. femur of the thigh. b. frontal bone of the forehead. in long bone formation, from what embryonic structure does the articular hyaline cartilage on the end of an ...Partially. Intramembranous Ossification Correctly sequence the steps of intramembranous ossification. Partially differentiated cells enlarge and differentiate into osteoblasts. Osteoblasts on the inside of the periosteum deposit compact bone over the spongy bone Connective tissue on the surface of each developing structure forms a periosteum ...Steps of bone deposition. ... Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification? Ossification center develops > Calcification > Formation of trabeculae > Development of new …Place the events in the proper sequence in which they occur during intramembranous ossification. osteoblasts form and produce osteoid, bone tissues expands to form spicules, vessels are trapped by growing spicules, continuous plate of spongy bone to forms ... He can correctly say that the x-ray film is from an individual who _____.Osteoblasts build the bone collar on the external surface of the bone. 3. Perichondrium is invaded by blood vessels. 4. In the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone. 5. Perichondrial cells differentiate into osteogenic cells then into osteoblasts. 3, 5, 2, 1, 4.Steps of intramembranous bone formation. aggregation of undifferentiated mesenchymal cells; osteoblast differentiation; organic matrix depositionintramembranous step 1. ossification center of osteoblasts forms in fibrous connective tissue. (formed by mesenchymal cells) intramembranous step 2. bone matrix (osteoid) is secreted by osteocytes in fibrous membrane. intramembranous step 3. osteoid is laid down between blood vessels= network of trabeculae. vascularized mesenchyme …1/2. Synonyms: none. Endochondral ossification is one of the two ways by which bone is formed. The process of bone formation and development begins as an embryo and continues until early adulthood. Endochondral ossification occurs in the long bones around the 6th embryonic week. It involves the formation of hyaline cartilage precursors from ...The steps of intramembranous ossification are shown in Figure 2. Figure 2 Steps of intramembranous ossification: ossification center appears in fibrous connective tissue membrane (A), bone matrix is secreted (B), woven bone and periosteum form (C), bone collar of compact bone forms and marrow appears (D). Choose the steps of intramembranous ossification in order to accurately reflect the sequence of events. This problem has been solved! You'll get a detailed solution that helps you learn core concepts. Intramembranous ossification is the process by which flat bones are formed. For this process, osteoblasts differentiate directly from mesenchymal cells to form the bone matrix. Long bones are formed by endochondral ossification, which is characterized by the presence of a cartilaginous model in which chondrocytes differentiate and mineralized ...Matador is a travel and lifestyle brand redefining travel media with cutting edge adventure stories, photojournalism, and social commentary. LATELY, ELEPHANT-BASED TOURISM has infl... Anatomy and Physiology questions and answers. Endochondral Ossification Correctly sequence the steps of endochondral ossification. Osteoblasts beneath the periosteum deposit a thin layer of compact bone. Cartilage tissue breaks down while the periosteum develops Blood vessels and osteoblasts from the penosteum invade the disintegrating tissue. Step 1. Here's an explanation of the steps involved in endochondral ossification, the process by which most ... View the full answer Step 2. Unlock. Answer. Unlock. Previous question Next question. Transcribed image text: Place the steps of endochondral ossification in the correct order from first to last.Bringing order and understanding to unstructured information located across disparate silos has been one of the more significant breakthroughs of the big data era, and today a Euro...Question: Choose the steps of intramembranous ossification in order to accurately reflect the sequence of events. Choose the steps of intramembranous ossification in order to accurately reflect the sequence of events. Here’s the …Recognize different bone cell types: osteoblasts, osteocytes, and osteoclasts. Know their role in the process of intramembranous bone formation. Have an understanding of bone remodeling over time (osteon formation) and long bones growth in length and width. Recognize mature and immature (mottled or woven) bone in light micrographs.Intramembranous Ossification. Intramembranous ossification mainly occurs during the formation of the flat bones of the skull, as well as the mandible, maxilla, and clavicles. The bone is formed from connective tissue such as mesenchyme tissue rather than from cartilage. The steps in intramembranous ossification are: …Figure 6.4.1 – Intramembranous Ossification: Intramembranous ossification follows four steps. (a) Mesenchymal cells …Fig 1 – Steps of Intramembranous Ossification, in sequence from (A) to (D) Endochondral Ossification. Endochondral ossification is a process where bone forms by replacing a hyaline cartilage precursor. This occurs in the long bones. Fig 2 – Endochondral Ossification.Fibonacci numbers create a mathematical pattern found throughout nature. Learn where to find Fibonacci numbers, including your own mirror. Advertisement Is there a magic equation t...Term. Place the following images into the correct order to represent the sequence of the steps of endochondral ossification. A deficit of appositional bone growth. Stage 1. Deposition of osteoid tissue into embryonic mesenchyme. Stage 2. Calcification of osteoid tissue and entrapment of osteocytes. Stage 3.Study with Quizlet and memorize flashcards containing terms like Which of the following correctly lists the steps of fracture repair in sequence?, A sternal puncture is often employed to obtain a sample of, The components of the pelvic girdle are called and more.Endochondral ossification takes much longer than intramembranous ossification. Bones at the base of the skull and long bones form via endochondral ossification. In a long bone, for example, at about 6 to 8 weeks after conception, some of the mesenchymal cells differentiate into chondrocytes (cartilage cells) that form the cartilaginous skeletal ...Bone ossification, or osteogenesis, is the process of bone formation. This process begins between the sixth and seventh weeks of embryonic development and continues until about age twenty-five; although this varies slightly based on the individual. There are two types of bone ossification, intramembranous and endochondral. Each of these processes begins with a mesenchymal tissue precursor, but ...In addition, the SSCs were identified in the long bones of mice and humans, bones that form through endochondral ossification. However, different skeletal compartments develop through distinct processes; for example, bones of the skull use intramembranous ossification in development and repair 38. Whether the identity of the SSC is shared ...Intramembranous ossification of non-vault bones (e.g., bones of the facial skeleton) is not well described. ... Remodeling of the bony region is the last step in the process. Open in a separate window. Figure 4. Schematic of the cellular zones of distraction osteogenesis. The fibrous interzone (FIZ) forms first and is composed of a variety of ...Isolated lissencephaly sequence (ILS) is a condition that affects brain development before birth. Explore symptoms, inheritance, genetics of this condition. Isolated lissencephaly ...Ossification, also known as osteogenesis, is the process of bone formation, where mesenchymal cells differentiate into osteoblasts that lay down new bone tissue. There are two types of ossification: intramembranous, which directly converts mesenchymal tissue into bone, and endochondral, which involves the transformation of … Correctly sequence the steps of intramembranous ossification: Connective tissue on the surface of each developing structure forms a periosteum. Partially differentiated cells enlarge and differentiate into osteoblasts. Osteoblasts deposit bone matrix, forming spongy bone tissue. Membranelike layers of connective tissue appear at sites of future ... Step 1. Intramembranous ossification is an essential process involved in the formation and remodeling of bon... ( 150 Uncalcified Calcium salts in organic matrix the calcified bone Mesenchymal Osteogenic cells cells Collagen fibers s ecreting Early compact bone Early spongy bone ob Trabeculae alearly organic matrix spongy bone Osteocytes ...Study with Quizlet and memorize flashcards containing terms like Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification? A) Ossification center develops > Calcification > Formation of trabeculae > Development of new periosteum. B) Calcification > Ossification center develops > …The following are major steps in the process of intramembranous ossification: 1. Trabecular matrix and periosteum form. 2. Secreted osteoid traps osteoblasts, which then become osteocytes. 3. Compact bone develops superficial to the trabecular bone. 4. Mesenchymal cells group into clusters, and ossification centers form.In mice, these differentiated cartilage structures appear around embryonic day 12, with the limb elements emerging in sequence along the proximodistal axis (i.e., hip to toes, shoulder to fingers). The sequential steps of the endochondral ossification process starting from this stage are illustrated in Figure 60-1. Initially, the cartilage ...step two. cartilage tissue breaks down. periosteum develops. step three. blood vessels and differentiating osteoblasts from the periosteum invade the disintegrating tissue. step five. osteoblasts beneath the periosteum deposit a thin layer of compact bone. step six. osteoblasts become osteocytes when bony matrix completely sorrounds them. steps ...Endochondral ossification takes much longer than intramembranous ossification. Bones at the base of the skull and long bones form via endochondral ossification. In a long bone, for example, at about 6 to 8 weeks after conception, some of the mesenchymal cells differentiate into chondrocytes (cartilage cells) that form the cartilaginous skeletal ...Question: 34) Sequence the following events of intramembranous ossification, ots) (Click and drag to put the items in the correct order, or click here to recorder by entering numbers directly 1 the periosteum is formed from other mesenchymal cells 2 > spongy bone is formed and innervated by blood vessels 3 > begin with the dense fibrous CT template …Correctly order the following key steps in the process of endochondral ossification. 1.Chondrocytes die. 2.Osteoblasts build the bone collar on the external surface of the bone. 3.Perichondrium is invaded by blood vessels. 4.In the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone. 5.Perichondrial cells differentiate into osteogenic cells then into ...Citation, DOI, disclosures and article data. Intramembranous ossification describes the process of ossification from mesenchymal cells (stem cells) without a cartilaginous template and is involved in the healing process of fractures. The stages of intramembranous ossification osteogenesis are as follows:Step 1. Arrange the steps of endochondral ossification and epiphyseal bone growth in the correct order. There is no time limit and you have unlimited attempts to get them all correct. There is no partial credit, so make sure to think carefully and learn from any mistakes. 1 1 10 1 Below are steps of endochondral ossification and epiphyseal bone ...Whole exome sequencing and whole genome sequencing are methods to rapidly identify genetic variations. Learn more about these forms of genetic sequencing. Determining the order of ...Although several limitations need to be overcome, this work is an important first step to understand the human intramembranous ossification process. In addition, the system is expected to contribute to understanding of human osteocyte biology and osteocyte-related diseases, and thereby the development of novel therapeutics in … The first step in intramembranous ossification is the formation of mesenchymal condensations, which differentiate into proliferating preosteoblasts and finally become bone-depositing osteoblasts (Fig. 7.1 B). The flat bones of the skull are formed in connective tissue layers called the skeletogenic membrane, which is located between the dura ... Whole genome sequencing can analyze a baby's DNA and search for mutations that may cause health issues now or later in life. But how prepared are we for this knowledge and should i...May 18, 2021 · The flat bones of the face, most of the cranial bones, and the clavicles (collarbones) are formed via intramembranous ossification. The process begins when mesenchymal cells in the embryonic skeleton gather together and begin to differentiate into specialized cells (Figure 5.4.1.a 5.4. 1. Intramembranous Ossification. Get a hint. Step 1. Click the card to flip 👆. Development of Ossification Center: -Osteoblasts secrete extracellular matrix of bone (osteoid) --Become surrounded by it. Click the card to flip 👆. 1 / 8.Intramembranous Ossification. Intramembranous ossification mainly occurs during the formation of the flat bones of the skull, as well as the mandible, maxilla, and clavicles. The bone is formed from connective tissue such as mesenchyme tissue rather than from cartilage. The steps in intramembranous ossification are: Development of ossification ...Blood cells are made in the red bone marrow of bones, a process known as:MGA Thermal co-founders Erich Kisi and Alex Post. Image Credits: MGA Thermal MGA Thermal co-founders Erich Kisi and Alex Post. Image Credits: MGA Thermal MGA Thermal wants to help ...What are the stages of intramembranous ossification? Hint : 4 steps. ... Stages of intramembranous ossification: 1 An ossification center appears in the _____ 2 Bone matrix is secreted within the _____ 3 Woven bone and _____ form 4 Bone collar of compact bone forms, and red marrow appears. OSTEOCYTE *- is a mature bone cell which is …What are the stages of intramembranous ossification? Hint : 4 steps. ... Stages of intramembranous ossification: 1 An ossification center appears in the _____ 2 Bone matrix is secreted within the _____ 3 Woven bone and _____ form 4 Bone collar of compact bone forms, and red marrow appears. OSTEOCYTE *- is a mature bone cell which is …Intramembranous ossification is characterized by the formation of bone tissue directly from mesenchyme. Flat bones, such as the parietal and occipital bones, are formed using this process. On the contrary, endochondral ossification is dependent on a cartilage model. Long and short bones, such as the femur and phalanges, arise from a … Q-Chat. Study with Quizlet and memorize flashcards containing terms like first step of intramembranous ossification, Second step of intramembranous ossification, third step of intramembranous ossification and more. Cell biology. endochondral bone formation occurs with a cartilage model. chondrocytes produce cartilage which is absorbed by osteoclasts. osteoblasts lay down bone on cartilaginous framework (bone replaces cartilage, cartilage is not converted to bone) forms primary trabecular bone. bone deposition occurs on metaphyseal side.The second type of ossification also occurs in the fetus; this is intramembranous ossification; this is the process by which mesenchymal tissue (primitive connective tissue) is converted directly to the bone, which no cartilage intermediate. This process takes place in the flat bones of the skull.Discover the intramembranous ossification steps, the cells involved in the process, and what differentiates intramembranous ossification from endochondral …6 Steps in Endochondral Ossification. Get a hint. What is the 1st step in Endochondral Ossification? Click the card to flip 👆. (8-12 week period) - Fetal hyaline cartilage model develops. Click the card to flip 👆. 1 / 6.Correctly sequence the steps of intramembranous ossification: Connective tissue on the surface of each developing structure forms a periosteum. Partially differentiated cells enlarge and differentiate into osteoblasts. Osteoblasts deposit bone matrix, forming spongy bone tissue. Membranelike layers of connective tissue appear at sites of future ...Study with Quizlet and memorize flashcards containing terms like Which of the following best describes osseous tissue?, Place the following stages into the correct spaces to represent the chronological order of intramembranous ossification:, Osseous tissue matrix is composed of _____. and more.Osteoblasts build the bone collar on the external surface of the bone. 3. Perichondrium is invaded by blood vessels. 4. In the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone. 5. Perichondrial cells differentiate into osteogenic cells then into osteoblasts. 3, 5, 2, 1, 4.Intramembranous ossification is the process by which flat bones are formed. For this process, osteoblasts differentiate directly from mesenchymal cells to form the bone matrix. Long bones are formed by endochondral ossification, which is characterized by the presence of a cartilaginous model in which chondrocytes …Question: Correctly sequence the steps of endochondral ossification.Blood vessels and osteoblasts from the periosteum invade the disintegrating tissue.Masses of hyaline cartilage form models of the future bones.Osteoblasts beneath the periosteum deposit a thin layer of compact bone.Osteoblasts form spongy bone in the space occupied by …However, different skeletal compartments develop through distinct processes; for example, bones of the skull use intramembranous ossification in development and repair 38. Whether the identity of ...Go to: Intramembranous ossification is the characteristic way in which the flat bones of the skull and the turtle shell are formed. During intramembranous ossification in the skull, neural crest-derived …articular cartilage. Which of the following is the correct sequence of steps in the repair of a bone fracture? fracture hematoma, fibrocartilaginous callus formation, bony callus formation, bone remodeling. Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification?Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification? Entry field with correct answer Ossification center develops > Calcification > Formation of trabeculae > Development of new periosteum. Calcification > Ossification center develops > Formation of trabeculae > Development …The ________ is the enlarged, rounded end of a long bone. 3, 5, 2, 1, 4. Correctly order the following key steps in the process of endochondral ossification. 1. Chondrocytes die. 2. Osteoblasts build the bone collar on the external surface of the bone.Anatomy and Physiology questions and answers. Place the events of intramembranous ossification in the order in which they occur. 1. Development of an ossification center inside of the fibrous membrane (mesenchyme). 2. Mesenchymal cells differentiate and the periosteum is formed. 3. Bone matrix secreted osteoblast forming early spongy bone.Medicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine ARTICLE: Transcriptional profile of platelets and iPSC-derived megakaryocytes from...
Choose the steps of intramembranous ossification in order to accurately reflect the sequence of events. This problem has been solved! You'll get a detailed solution that helps you learn core concepts.. Customer service meijer hours
Terms in this set (5) step 1. mesenchymal cells cluster and differentiate into osteoblasts. secrete bone matrix components that crystallize with calcium salts. step 2. some osteoblasts are trapped in the bone matrix and differentiate into osteocytes. bone grows spicules outward from ossification centers. step 3.Anatomy and Physiology. Anatomy and Physiology questions and answers. 5. Place the events of intramembranous ossification in order (0.5): A. Accumulating osteoid is laid down between embryonic blood vessels in a random manner and mesenchymal cells condense around the bone material to form the periosteum. B.Intramembranous ossification. Intramembranous ossification forms flat and irregular bones. In this process, mesenchymal cells differentiate directly into osteoblasts; specialized cells that secrete bone matrix. As the osteoblasts are housed within the matrix they secrete, they become progressively distanced from each other but remain connected ... The ________ is the enlarged, rounded end of a long bone. 3, 5, 2, 1, 4. Correctly order the following key steps in the process of endochondral ossification. 1. Chondrocytes die. 2. Osteoblasts build the bone collar on the external surface of the bone. DNA Mutation, Variation and Sequencing - DNA mutation is essentially a mistake in the DNA copying process. Learn about DNA mutation and find out how human DNA sequencing works. Adv...Study with Quizlet and memorize flashcards containing terms like Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification? Entry field with correct answer Ossification center develops > Calcification > Formation of trabeculae > Development of new periosteum. Calcification > Ossification center develops > Formation of trabeculae ...Endochondral Ossification Correctly sequence the steps of endochondral ossification. Osteoblasts beneath the periosteum deposit a thin layer of compact bone. Cartilage tissue breaks down while the periosteum develops Blood vessels and osteoblasts from the penosteum invade the disintegrating tissue.Bone ossification, or osteogenesis, is the process of bone formation. This process begins between the sixth and seventh weeks of embryonic development and continues until about age twenty-five; although this varies slightly based on the individual. There are two types of bone ossification, intramembranous and endochondral. Each of these processes begins with a mesenchymal tissue precursor, but ...Jun 18, 2021 · Cell biology. endochondral bone formation occurs with a cartilage model. chondrocytes produce cartilage which is absorbed by osteoclasts. osteoblasts lay down bone on cartilaginous framework (bone replaces cartilage, cartilage is not converted to bone) forms primary trabecular bone. bone deposition occurs on metaphyseal side. Answer and Explanation: 1. Most bones in the human body originate from hyaline cartilage in a process known as endochondral ossification. This process, reflected in the development of the femur in figure 1 below, occurs in the following sequence: Chondrocytes in the center of the shaft of cartilage enlarge such that the extracellular matrix is ... [1] Light micrograph of a nidus consisting of osteoprogenitor cells that are displaying a prominent Golgi apparatus. The process of intramembranous ossification starts when a small group of adjacent MSCs begin to …Final answer: The correct sequence of intramembranous ossification involves the process starting from the differentiation of mesenchymal cells into osteoblasts, osteoblasts getting encased in the matrix, trapping of blood vessels within the bone matrix, and finally, the creation of a compact bone plate by the osteoblasts.. Explanation:Intramembranous ossification. Intramembranous ossification is the characteristic way in which the flat bones of the skull and the turtle shell are formed. During intramembranous ossification in the skull, neural crest-derived mesenchymal cells proliferate and condense into compact nodules. (Thus, intramembranous ossification is not occurring ...Correctly order the following key steps in the process of endochondral ossification. 1. Chondrocytes die. 2. Osteoblasts build the bone collar on the external surface of the bone. 3. Perichondrium is invaded by blood vessels. 4. In the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone. 5.Osteoblasts secrete extracellular matrix that surrounds them. Calcification: step 2. Matrix stops cells in the lacunae and extend their cytoplasmic processes into cannaliculi that radiate in all directions. Soon calcium and mineral salts are deposited and matrix calcifies and hardens. Formation of trabeculae: step 3. As matrix forms it develops ...Lifehacker is the ultimate authority on optimizing every aspect of your life. Do everything better.5. Mesenchyme on the surface condenses into periosteum. 6. Osteoblasts on the inside deposit compact bone over the spongy bone. Study with Quizlet and memorize flashcards containing terms like intramembranous bones, What are the steps in intramembranous ossification, What is the first step of intramembranous ossification and more. In reference to intramembranous ossification, decide on the proper order of the numbered steps below, and then choose the letter that lists the steps in correct sequence: 1. bits of bone, called trabeculae, develop and interconnect to form immature spongy bone 2. osteoblasts secrete unmineralized bone matrix called osteoid 3. mesenchyme cells differentiate into osteoblasts in the ossification ... The flat bones of the face, most of the cranial bones, and the clavicles (collarbones) are formed via intramembranous ossification. The process begins when mesenchymal cells in the embryonic skeleton gather together and begin to differentiate into specialized cells (Figure 6.5.1 6.5. 1 a )..
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